Mikael Knip Selected Research

Zinc Transporter 8

1/2021	Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes.
1/2021	Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk.
11/2020	HLA-DR-DQ haplotypes and specificity of the initial autoantibody in islet specific autoimmunity.
1/2020	Association of diabetes-related autoantibodies with the incidence of asthma, eczema and allergic rhinitis in the TRIGR randomised clinical trial.
1/2016	Positivity for Zinc Transporter 8 Autoantibodies at Diagnosis Is Subsequently Associated With Reduced β-Cell Function and Higher Exogenous Insulin Requirement in Children and Adolescents With Type 1 Diabetes.
8/2015	Circulating IGF1 and IGFBP3 in relation to the development of β-cell autoimmunity in young children.
11/2010	Dietary intervention in infancy and later signs of beta-cell autoimmunity.

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Mikael Knip Research Topics

Disease

220	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2022 - 01/2002
23	Infections 11/2021 - 01/2003
16	Celiac Disease (Celiac Sprue) 05/2022 - 06/2003
13	Disease Susceptibility (Diathesis) 01/2022 - 02/2004
13	Enterovirus Infections 01/2021 - 01/2003
12	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 05/2002
11	Asthma (Bronchial Asthma) 01/2022 - 10/2011
9	Genetic Predisposition to Disease (Genetic Predisposition) 01/2022 - 10/2006
8	Hypersensitivity (Allergy) 01/2022 - 05/2011
8	Insulinoma 01/2021 - 01/2007
7	Type 2 Diabetes Mellitus (MODY) 11/2021 - 10/2004
7	Epilepsy (Aura) 05/2010 - 05/2002
5	Disease Progression 01/2022 - 09/2010
5	Milk Hypersensitivity (Milk Allergy) 11/2021 - 08/2014
5	Allergic Rhinitis 11/2021 - 01/2013
5	Insulin Resistance 01/2015 - 08/2002
4	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2022 - 11/2011
4	Inflammation (Inflammations) 01/2022 - 04/2013
4	Atopic Dermatitis (Atopic Eczema) 01/2021 - 01/2013
4	Prodromal Symptoms 11/2017 - 12/2005
4	Obesity 09/2006 - 05/2002
4	Weight Gain 09/2006 - 04/2002
3	Body Weight (Weight, Body) 01/2021 - 05/2002
3	Virus Diseases (Viral Diseases) 01/2020 - 08/2006
3	Hyperinsulinism (Hyperinsulinemia) 09/2006 - 05/2002
2	Eczema 01/2021 - 01/2020
2	Rhinitis 01/2021 - 01/2020
2	Birth Weight (Birth Weights) 01/2021 - 07/2012
2	Dysbiosis 01/2020 - 01/2017
2	Adenoviridae Infections (Adenovirus Infections) 01/2020 - 08/2006
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2018 - 12/2005
2	Glucose Intolerance 01/2017 - 08/2015
2	Atrophy 11/2016 - 12/2003
2	Prediabetic State (Prediabetes) 04/2015 - 01/2002
2	Chronic Disease (Chronic Diseases) 08/2014 - 10/2011
2	Otitis Media 11/2011 - 07/2008
2	Gestational Diabetes (Gestational Diabetes Mellitus) 12/2008 - 03/2006
2	Hyperandrogenism 09/2006 - 05/2002

Drug/Important Bio-Agent (IBA)

111	AutoantibodiesIBA 01/2022 - 01/2002
67	Insulin (Novolin)FDA Link 01/2022 - 01/2002
45	AntibodiesIBA 01/2022 - 01/2002
36	1,3-di(4-imidazolinophenoxyl)propaneIBA 01/2022 - 01/2003
22	AntigensIBA 01/2021 - 01/2002
20	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 01/2022 - 01/2002
17	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 09/2006
16	Proteins (Proteins, Gene)FDA Link 08/2021 - 05/2002
14	Immunoglobulin G (IgG)IBA 01/2020 - 02/2004
11	Biomarkers (Surrogate Marker)IBA 05/2022 - 04/2002
11	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 12/2008
10	AutoantigensIBA 01/2012 - 01/2002
9	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 12/2011
9	Immunoglobulin E (IgE)IBA 11/2021 - 01/2010
9	HLA-DQB1 antigen (HLA DQB1)IBA 01/2021 - 03/2002
8	Vitamin D FDA LinkGeneric 01/2020 - 06/2006
7	Zinc Transporter 8IBA 01/2021 - 11/2010
7	HLA-DR Antigens (HLA-DR)IBA 11/2020 - 03/2006
6	HLA-DQ Antigens (HLA-DQ)IBA 01/2021 - 01/2005
6	EpitopesIBA 11/2019 - 01/2002
6	LipidsIBA 01/2019 - 07/2005
6	VaccinesIBA 12/2018 - 11/2011
5	Glutens (Glutelin)IBA 01/2020 - 07/2012
5	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2020 - 06/2003
5	Immunoglobulin A (IgA)IBA 01/2020 - 09/2007
5	Dietary ProteinsIBA 10/2019 - 11/2010
5	Peptides (Polypeptides)IBA 05/2015 - 11/2005
5	Protein Tyrosine PhosphatasesIBA 01/2007 - 06/2003
4	CytokinesIBA 01/2022 - 08/2008
4	Biological ProductsIBA 11/2021 - 04/2014
4	Caseins (Casein)FDA Link 08/2021 - 06/2014
4	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 01/2002
4	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 01/2002
4	ProinsulinIBA 01/2020 - 11/2005
4	25-hydroxyvitamin DIBA 01/2020 - 11/2014
4	EnzymesIBA 01/2019 - 12/2002
4	RNA (Ribonucleic Acid)IBA 01/2018 - 07/2008
4	AllergensIBA 05/2011 - 01/2010
4	Valproic Acid (Depakote)FDA LinkGeneric 09/2006 - 05/2002
3	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2022 - 04/2013
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 11/2021 - 12/2011
3	TransglutaminasesIBA 01/2018 - 10/2005
3	casein hydrolysateIBA 01/2018 - 11/2010
3	GliadinIBA 05/2015 - 09/2007
3	Immunoglobulin M (IgM)IBA 04/2014 - 06/2012
2	MicroRNAs (MicroRNA)IBA 01/2022 - 11/2015
2	alpha-Linolenic Acid (Linolenic Acid)IBA 11/2021 - 12/2011
2	AntioxidantsIBA 01/2021 - 08/2008
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021 - 04/2002
2	Phospholipids (Phosphatides)FDA LinkGeneric 10/2020 - 09/2013
2	Amino Acids FDA Link 12/2019 - 12/2008
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2019 - 01/2017
2	hydroxide ionIBA 01/2019 - 11/2014
2	Indicators and Reagents (Reagents)IBA 04/2016 - 10/2004
2	C-PeptideIBA 01/2016 - 09/2006
2	Advanced Glycation End ProductsIBA 04/2015 - 10/2011
2	Interleukin-17 (Interleukin 17)IBA 01/2015 - 08/2010
2	Palmitic Acid (Hexadecanoic Acid)IBA 03/2014 - 12/2011
2	Neutralizing AntibodiesIBA 07/2008 - 04/2007
2	Pharmaceutical PreparationsIBA 06/2008 - 12/2003

Therapy/Procedure

6	Therapeutics 01/2022 - 05/2002
3	Glycemic Control 01/2020 - 07/2008